Wednesday, February 26th 2020

Member Publications

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Charité Campus Mitte
University of Debrecen
Liverpool John Moores University
University of Murcia
Institute of General Pathology CU Rome
Institute of Biochemistry CU Rome
Deutsche Herzstiftung
Juver Alimentación S.A.

Caledonian Science Press

UNI Debrecen Publications

1. Foerster M., Sass J. O., Rühl R., Nau H. (1996) Toxicol. in vitro 10: 7-15. “Comparative studies on effects of all-trans-retinoic acid and all-trans-retinoyl-ß-D-glucuronide on the development of foetal mouse thymus in an organ culture system”.

2. Sass, J. O., Zimmermann B., Rühl R., Nau H. (1996) Arch. Toxicol. 71: 142-150. “Effects of all-trans-retinoyl-ß-D-glucuronide and all-trans-retinoic acid on chondrogenesis and retinoid metabolism in mouse limb bud mesenchymal cells in vitro”.

3. Nau H., Elmazar M.M.A., Rühl R., Thiel R., Sass J. O. (1996) Teratology 54: 150-156. “All-trans-retinoyl-ß-glucuronide is a potent teratogen in mouse because of extensive metabolism to all-trans-retinoic acid”.

4. Rühl R., Nau H. (1997) Chromatographia 45: 269-274. “Determination of Adapalene (CD271/Differine) and retinol in plasma and tissue by online solid-phase extraction and HPLC analysis”.

5. Elmazar M. M. A., Rühl R., Reichert U., Shroot B., Nau H. (1997) Toxicol. Appl. Pharmacol. 146: 21-28 “RAR-mediated teratogenicity in mice is potentiated by an RXR agonist and reduced by an RAR agonist: Dissection of retinoid receptor-induced pathways”.

6. Zouboulis C.C., Xia L., Akamatsu H., Seltmann H., Fritsch M., Hornemann S., Rühl R., Chen W., Orfanos C.E. (1998) Dermatology 1996: 21-31. “The human sebocyte culture model provides new insights into development and management of seborrhoea and acne”.

7. Zouboulis C.C., Seltmann H., Sass J.O., Rühl R., Plum C., Hettmannsperger U., Blume-Peytavi U., Nau H., Orfanos C.E. (1999) J. Invest. Dermatol. 112: 157-164. “Autoregulatory mechanisms against an excessive accumulation of all-trans-retinoic acid determine the interactions of retinol with all-trans-retinoyl-ß-D-glucuronide in cultured human keratinocytes”.

8. Arnhold T., Rühl R., Nau H. (2000) p. 3-50, Song W.O., Beecher G.R., Eitenmiller R.R. (EDS.); Modern analytical methodologies on fat and water-soluble vitamins; John Wiley & Sons, New York, Chemical Analysis series, Volume 154, ISBN 0-471-17942-6. “Vitamin A”.

9. Elmazar M.M.A., Rühl R., Nau H. (2001) Toxicol. Appl. Pharmacol. 170: 2-9. “Synergistic teratogenic effects induced in mice by coadministration of an RAR?- or RAR ?-selective agonist with a RXR-selective agonist”.

10. Rühl R., Thiel R., Lacker T., Strohschein S., Albert K., Nau H. (2001) J. Chrom. B. 757, 101-109. “Synthesis, high performance liquid chromatography-nuclear magnetic resonance characterisation and pharmacokinetics in mice of CD271-glucuronide”.

11. Rühl R., Elmazar M.M.A., Nau H. (2001) Tox. Sci. 63, 82-89. “Embryonic subcellular distribution of 13-cis- and all-trans-retinoic acid indicates differential cytosolic / nuclear localisation”.

12. Rühl R., Sass J. O., Nau H., Klug S. (2001) Arch. Tox. 75, 497-504. “Effects of all-trans-retinoic acid and all-trans-retinoyl glucuronide in two in vitro systems of distinct biological complexity”.

13. Landes N., Pfluger P., Kluth D., Birringer M., Rühl R., Böl G.-F., Glatt H., Brigelius-Flohé R. (2003). Biochem. Pharmacol. 65, 269-273. „Vitamin E as an activator of gene expression via the pregnan-X-receptor“.

14. Rühl R., Dahten A., Herz U., Schweigert F. J., Worm M. (2003). Invest. Dermatol. 121, 757-764. „Inhibition of IgE production by peroxisome proliferator-activated receptor ligands“.

15. Garcia A.L., Rühl R., Herz U., Anton K., Schweigert F.J., Worm M. (2003) Immunology 110, 180-187.  „Retinoid and carotenoid enriched diets influence the ontogenesis of the immune system“.

16. Rühl R., Schweigert F.J. (2003) J. Chrom. B. 798, 309-316. “Fully automated solid-phase extraction method and retinoid HPLC analysis“.

17. Rühl R., Garcia A., Schweigert F.J., Worm M. (2004) Int. J. Vitam. Nutr. Res. 74, 279-284. „Modulation of cytokine production by low and high retinoid diets in OVA sensitized mice“.

18. Rühl R., Sczech R., Landes N., Pfluger P., Schweigert F.J. (2004)-  Eur. J. Nutr. 43, 336-343. „Carotenoids and their metabolites are naturally occurring activators of gene expression via pregnan X receptor“.

19. Szanto A., Benko S., Szatmari I., Balint L.B., Furtos I., Rühl R., Molnar S., Csiba L., Garuti R., Calandra S., Larsson H., Diczfalusy U., Nagy L. (2004) Mol. Cell. Biol. 24, 8154-8166 „Transcriptional regulation of human CYP27 integrates retinoid, PPAR and LXR signalling leading to cholesterol efflux from macrophages“.

20. Rühl R., Hamscher G., Garcia A., Nau H., Schweigert F.J. (2005) Life Sci. 76, 1613-1622. „Identification of 14-hydroxy-retro-retinol and 4-hydroxy-retinol as novel endogenous retinoids in mammalians throughout neonatal development“.

21. Rühl R Biochem. Biophys. Acta. (in press) “Induction of PXR-mediated metabolism by ß-carotene”.